SWVRC Fianance, Loans & Debt

Main Menu

  • Home
  • Coefficient of Variation
  • Temporal
  • Nasdaq
  • MSCIWI
  • Debt

SWVRC Fianance, Loans & Debt

Header Banner

SWVRC Fianance, Loans & Debt

  • Home
  • Coefficient of Variation
  • Temporal
  • Nasdaq
  • MSCIWI
  • Debt
Coefficient of Variation
Home›Coefficient of Variation›Mid-regional proadrenomedullin, C-terminal proendothelin-1 values, and disease course are not different in critically ill SARS-CoV-2 pneumonia patients with obesity

Mid-regional proadrenomedullin, C-terminal proendothelin-1 values, and disease course are not different in critically ill SARS-CoV-2 pneumonia patients with obesity

By Maureen Bellinger
July 15, 2022
0
0
  • Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506.

    CAS 
    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054–62.

    CAS 
    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 2020;8:475–81.

    CAS 
    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, et al. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region, Italy. JAMA. 2020;323:1574–81.

    CAS 
    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Bhatraju PK, Ghassemieh BJ, Nichols M, Kim R, Jerome KR, Nalla AK, et al. COVID-19 in critically ill patients in the Seattle region – case series. N Engl J Med. 2020;382:2012–22.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Gupta S, Hayek SS, Wang W, Chan L, Mathews KS, Melamed M, et al. Factors associated with death in critically ill patients with coronavirus disease 2019 in the US. JAMA Intern Med. 2020;180:1436–47.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Simonnet A, Chetboun M, Poissy J, Raverdy V, Noulette J, Duhamel A, et al. High prevalence of obesity in severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation. Obesity. 2020;28:1195–9.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Caussy C, Wallet F, Laville M, Disse E. Obesity is associated with severe forms of COVID-19. Obesity. 2020;28:1175.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Ni W, Yang X, Yang D, Bao J, Li R, Xiao Y, et al. Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19. Crit Care. 2020;24:422.

    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Kruglikov IL, Scherer PE. The role of adipocytes and adipocyte-like cells in the severity of COVI-19 infections. Obesity. 2020;28:1187–90.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Kooistra EJ, de Nooijer AH, Claassen WJ, Grondman I, Janssen NAF, Netea MG, et al. A higher BMI is not associated with a different immune response and disease course in critically ill COVID-19 patients. Int J Obes. 2021;45:687–94.

    CAS 
    Article 

    Google Scholar 

  • Wilson DC, Schefold JC, Baldirà J, Spinetti T, Saeed K, Elke G. Andrenomedullin in COVID-19 induced endotheliitis. Crit Care. 2020;24:411.

    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Varga Z, Flammer AJ, Steiger P, Haberecker M, Andermatt R, Andermatt R, et al. Endothelial cell infection and endotheliitis in COVID-19. Lancet. 2020;395:1417–8.

    CAS 
    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Struck J, Tao C, Morgenthaler NG, Bergman A. Identification of an adrenomedullin precursor fragment in plasma of sepsis patients. Peptides. 2004;25:1369–72.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Papassotiriou J, Morgenthaler NG, Struck J, Alanso C, Bergmann A. Immunoluminometric assay for measurement of the C-terminal Endothelin-1 precursor fragment in human plasma. Clin Chem. 2006;52:1144–51.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Temmesfeld-Wollbrück B, Hocke AC, Suttorp N, Hippenstiel S. Adrenomedullin and endothelial barrier function. Thromb Haemost. 2007;98:944–51.

    PubMed 
    Article 
    CAS 

    Google Scholar 

  • Temmesfeld-Wollbrück B, Brell B, Dávid I, Dorenberg M, Adolphs J, Schmeck B, et al. Adrenomedullin reduces vascular hyperpermeability and improves survival in rat septic shock. Intensive Care Med. 2007;33:703–10.

    PubMed 
    Article 
    CAS 

    Google Scholar 

  • Li Y, Jiang C, Wang X, Zhang Y, Shibahara S, Takahashi K, et al. Andrenomedullin is a novel adipokine: adrenomedullin in adipocytes and adipose tissues. Peptides. 2007;28:1129–43.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Teder P, Noble P. A cytokine reborn? Endothelin-1 in pulmonary inflammation and fibrosis. Am J Cell and Mol Biol. 2000;23:7–10.

    CAS 
    Article 

    Google Scholar 

  • Weil BR, Westby CM, Van Guilder GP, Greiner JJ, Stauffer BL, DeSouza CA. Enhanced endothelin-1 system activity with overweight and obesity. Am J Physiol Heart Circ Physiol. 2011;301:H689–H695.

    CAS 
    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Engin A. Endothelial dysfunction in obesity. Adv Exp Med Biol. 2017;960:345–79.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Van Oers JAH, Kluiters Y, Bons JAP, de Jongh M, Pouwels S, Ramnarain D, et al. Endothelium-associated biomarkers mid-regional proadrenomedullin and C-terminal proendothelin-1 have good ability to predict 28-day mortality in critically ill patients with SARS-C0V-2 pneumonia: a prospective cohort study. J Crit Care. 2021;66:173–89.

    PubMed 
    PubMed Central 
    Article 
    CAS 

    Google Scholar 

  • WHO. Clinical management of COVID-19. May 27. 2020. https://www.who.int/publications/i/item/clinical-management-of-covid-19. Accessed 11 Jan 2021.

  • World Health Organization. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser. 2000;894:1–253.

    Google Scholar 

  • De Smet AM, Kluytmans JA, Cooper BS, Mascini EM, Benus RF, van der Werf TS, et al. Decontamination of the digestive tract and oropharynx in ICU patients. N Engl J Med. 2009;360:20–31.

    PubMed 
    Article 

    Google Scholar 

  • Von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP. The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. PLoS Med. 2007;4:e296.

    Article 

    Google Scholar 

  • ARDS Definition Task Force Ranieri VM, Rubensfeld GD, Thompson BT, Ferguson ND, Caldwell E. et al. Acute respiratory distress syndrome: the Berlin definition. JAMA. 2012;307:2526–33.

    Google Scholar 

  • Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384:766–81.

    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Appachi S, Kelly KR, Schauer PR, Kirwan JP, Hazen S, Gupta M, et al. Reduced cardiovascular risk following bariatric surgeries is related to a partial recovery from adiposopathy. Obes Surg. 2011;21:1928–36.

    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Fezeu L, Julia C, Henegar A, Bitu J, Hu FB, Grobbee DE, et al. Obesity is associated with higher risk of intensive care unit admission and death in influenza A (H1N1) patients: a systematic review and meta-analysis. Obes Rev. 2011;12:653–9.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Czernichow S, Beeker N, Rives-Lange C, Guerot E, Diehl JL, Katsahian S, et al. Obesity doubles mortality in patients hospitalized for SARS-CoV-2 in Paris hospitals, France: a cohort study on 5795 patients. Obesity. 2020;28:2282–9.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Garcia de Guadiana-Romualdo L, Calvo Nieves MD, Rodríguez Mulero MD, Calcerrada Alises I, Hernández Olivo M, Trapiello Fernández W, et al. MR-proADM as marker of endotheliitis predicts COVID-19 severity. Eur J Clin Invest. 2021;51:e13511.

    CAS 
    PubMed 

    Google Scholar 

  • Sozio E, Tascini C, Fabris M, D’Aurizio F, De Carlo C, Graziano E, et al. MR-proADM as prognostic factor of outcome in COVID-19 patients. Sci Rep. 2021;11:5121.

    CAS 
    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Montrucchio G, Sales G, Rumbolo F, Palmesino F, Fanelli V, Urbino C, et al. Effectiveness of mid-regional pro-adrenomedullin (MR-proADM) as prognostic marker in COVID-19 critically ill patients: an observational prospective study. PLoS One. 2021;16:e0246771.

    CAS 
    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Spoto S, Agro FE, Sambuco F, Travaglino F, Valeriani E, Fogolari M, et al. High value of mid-regional proadrenomedullin in COVID-19: a marker of widespread endothelial damage, disease severity and mortality. J Med Virol. 2020;93:2820–7.

    Article 
    CAS 

    Google Scholar 

  • Gregoriano C, Koch D, Kutz A, Haubitz S, Conen A, Bernasconi L, et al. The vasoactive peptide MR-pro-adrenomedullin in COVID-19 patients: an observational study. Clin Chem Lab Med. 2021;59:995–1004.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Benedetti L, Spinelli D, Callegari T, Bonometti R, Molinaro E, Novara E, et al. High levels of mid-regional proadrenomedullin in ARDS COVID-19 patients: the experience of a single, Italian center. Eur Rev Med Pharmacol Sci. 2021;25:1743–51.

    CAS 
    PubMed 

    Google Scholar 

  • Braun N, Hoess C, Kutz A, Christ-Crain M, Thomann R, Henzen C, et al. Obesity paradox in patients with community-acquired pneumonia: is inflammation the missing link? Nutrition. 2017;33:304–10.

    PubMed 
    Article 

    Google Scholar 

  • Van Oers J, Krabbe J, Kemna E, Kluiters Y, Vos P, De Lange D, et al. Mid-regional proadrenomedullin and mid-regional proatrial natriuretic peptide clearance predicts poor outcome better than single baseline measurements in critically ill patients with pneumonia: a retrospective cohort study. Cureus. 2021;13:e15285.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Schetz M, de jong A, Deane AM, Druml W, Hemelaar P, Pelosi P, et al. Obesity in the critically ill: a narrative review. Intensive Care Med. 2019;45:757–69.

    PubMed 
    Article 

    Google Scholar 

  • Pepper DJ, Sun J, Welsh J, Cui X, Suffredini AF, Eichacker PQ. Increased body mass index and adjusted mortality in ICU patients with sepsis or septic shock: a systematic review and meta-analysis. Crit Care. 2016;20:181.

    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Ball L, Serpa Neto A, Pelosi P. Obesity and survival in critically ill patients with acute respiratory distress syndrome: a paradox within the paradox. Crit Care. 2017;21:114.

    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Aldes PA, Savage PD. The obesity paradox: perception vs knowledge. Mayo Clin Proc. 2010;85:112–4.

    Article 

    Google Scholar 

  • Zamboni M, Mazzali G, Zoico E, Harris TB, Meigs JB, Di Francesco V, et al. Health consequences of obesity in the elderly: a review of four unresolved questions. Int J Obes. 2005;29:1011–29.

    CAS 
    Article 

    Google Scholar 

  • Dana R, Bannay A, Bourst P, Ziegler C, Losser MR, Gibot S, et al. Obesity and mortality in critically ill COVID-19 patients with respiratory failure. Int J Obes. 2021;45:2028–37.

    CAS 
    Article 

    Google Scholar 

  • Pouwels S, Ramnarain D, Aupers E, Rutjes-Weurding L, van Oers J. Obesity may not be associated with 28-day mortality, duration of invasive mechanical ventilation and length of intensive care unit and hospital stay in critically ill patients with severe acute respiratory syndrome coronavirus-2: A retrospective cohort study. Medicina. 2021;57:674.

    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Kooistra EJ, Brinkman S, van der Voort PHJ, de Keizer NF, Dongelmans DA, Kox M, et al. Body mass index and mortality in coronavirus disease 2019 and other diseases: a cohort study in 35,506 ICU patients. Crit Care Med. 2022;50:e1–e10.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Kotsis V, Stabouli S, Papakatsika S, Rizos Z, Parati G. Mechanisms of obesity-induced hypertension. Hypertens Rev. 2010;33:386–93.

    Article 

    Google Scholar 

  • Ouchi N, Parker JL, Lugus JL, Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol. 2011;11:85–97.

    CAS 
    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Vila G, Riedl M, Maier C, Struck J, Morgenthaler NG, Handisurya A, et al. Plasma MR-proADM correlates to BMI and decreases in relation to leptin after gastric bypass surgery. Obesity. 2009;17:1184–8.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Del RyS, Cabiati M, Bianchi V, Caponi L, Di Cecco P, Marchi B, et al. Mid-regional-pro-adrenomedullin plasma levels are increased in obsess adolescents. Eur J Nutr. 2016;55:1255–60.

    Article 
    CAS 

    Google Scholar 

  • Voors AA, Kremer D, Geven C, Ter Maaten JM, Struck J, Bergmann A, et al. Adrenomedullin in heart failure: pathophysiology and therapeutic application. Eur J Heart Fail. 2019;21:163–71.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Buendgens L, Yagmur E, Bruensing J, Herbers U, Baeck C, Trautwein C, et al. C-terminal proendothelin-1 (CT-proET-1) is associated with organ failure and predicts mortality in critically ill patients. J Intensive Care. 2017;5:25.

    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Suthahar N, Meems LMG, Groothof D, Bakker SJL, Gansevoort RT, van Veldhuisen DJ, et al. Relationship between body mass index, cardiovascular biomarkers and incident heart failure. Eur J Heart Fail. 2021;23:396–402.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Krintus M, Kozinski M, Braga F, Kubica J, Sypniewska G, Pantegghini M. Plasma midregional proadrenomedullin (MR-proADM) concentrations and their biological determinants in a reference population. Clin Chem Lab Med. 2018;56:1161–8.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Smith JG, Newton-Cheh C, Hedblad B, Struck J, Morgenthaler NG, Bergmann A, et al. Distribution and correlates of midregional proadrenomedullin in the general population. Clin Chem. 2009;55:1593–5.

    CAS 
    PubMed 
    Article 

    Google Scholar 

  • Baretella O, Chung SK, Xu A, Van Houtte PM. Pardoxical lack of increase in endothelin-1 levels in obese mice – possible role of endothelin-B receptors. Acta Pharmacol Sin. 2017;38:1699–1700.

    CAS 
    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Griffith GJ, Morris TT, Tudball MJ, Herbert A, Mancano G, Pike L, et al. Collider bias undermines our understanding of COVID-19 disease risk and severity. Nat Commun. 2020;11:5749.

    CAS 
    PubMed 
    PubMed Central 
    Article 

    Google Scholar 

  • Related posts:

    1. Predicting tissue-specific gene expression from complete blood transcriptome
    2. MRI biomarker to foretell LNM in T3 stage rectal carcinoma
    3. Medical Components Related to Excessive Glycemic Variability Outlined by
    4. Significance of RDW in predicting mortality in COVID‐19—An evaluation of 622 circumstances – Soni – – Worldwide Journal of Laboratory Hematology

    Categories

    • Coefficient of Variation
    • Debt
    • MSCIWI
    • Nasdaq
    • Temporal
    • Terms and Conditions
    • Privacy Policy