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Home›Coefficient of Variation›Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England

Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England

By Maureen Bellinger
March 25, 2021
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  • MRC Centre for Global Infectious Disease Analysis, Jameel Institute for Disease and Emergency Analytics, Imperial College London, London, UK

    Erik Volz, Swapnil Mishra, Robert Johnson, Lily Geidelberg, Wes R. Hinsley, Daniel J. Laydon, Manon Ragonnet-Cronin, Olivia Boyd, David Jorgensen, Katy Gaythorpe, Samir Bhatt & Neil M. Ferguson

  • Public Health England, London, UK

    Meera Chand, Gavin Dabrera, Ian Harrison, Nicholas J. Loman, Richard Myers, Natalie Groves, Elias Allara, Clare Pearson, Husam Osman, Andrew Bosworth, Esther Robinson, Peter Muir, Ian B. Vipond, Richard Hopes, Hannah M. Pymont, Stephanie Hutchings, Angie Lackenby, Tamyo Mbisa, Steven Platt, Shahjahan Miah, David Bibby, Carmen Manso, Jonathan Hubb, Mary Ramsay, Daniel Bradshaw, Alicia Thornton, Ulf Schaefer, Eileen Gallagher, David Lee, David Williams, Nicholas Ellaby, Hassan Hartman, Nikos Manesis, Vineet Patel, Chloe Bishop, Vicki Chalker, Juan Ledesma, Katherine A. Twohig & Susan Hopkins

  • Wellcome Sanger Institute, Cambridge, UK

    Jeffrey C. Barrett, Robert Amato, Cristina V. Ariani, Sónia Gonçalves, David K. Jackson, John Sillitoe, Dominic P. Kwiatkowski, Alex Alderton, Roberto Amato, Mathew A. Beale, Charlotte Beaver, Katherine L. Bellis, Emma Betteridge, James Bonfield, John Danesh, Matthew J. Dorman, Eleanor Drury, Ben W. Farr, Luke Foulser, Sonia Goncalves, Scott Goodwin, Marina Gourtovaia, Ewan M. Harrison, Dorota Jamrozy, Ian Johnston, Leanne Kane, Sally Kay, Jon-Paul Keatley, Dominic Kwiatkowski, Cordelia F. Langford, Mara Lawniczak, Laura Letchford, Rich Livett, Stephanie Lo, Inigo Martincorena, Samantha McGuigan, Rachel Nelson, Steve Palmer, Naomi R. Park, Minal Patel, Liam Prestwood, Christoph Puethe, Michael A. Quail, Shavanthi Rajatileka, Carol Scott, Lesley Shirley, Michael H. Spencer Chapman, Scott A. J. Thurston, Gerry Tonkin-Hill, Danni Weldon, Diana Rajan, Iraad F. Bronner, Louise Aigrain, Nicholas M. Redshaw, Stefanie V. Lensing, Robert Davies, Andrew Whitwham, Jennifier Liddle, Kevin Lewis, Jaime M. Tovar-Corona, Steven Leonard, Jillian Durham, Andrew R. Bassett, Shane McCarthy, Robin J. Moll, Keith James, Karen Oliver, Alex Makunin & Jeff Barrett

  • Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK

    Áine O’Toole, Ben Jackson, John T. McCrone, Verity Hill & Andrew Rambaut

  • Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK

    Nicholas J. Loman, Nicholas J. Loman, Joshua Quick, Claire McMurray, Joanne Stockton, Sam Nicholls, Will Rowe, Radoslaw Poplawski & Alan McNally

  • Department of Mathematics, Imperial College London, London, UK

    Seth Flaxman, Oliver Ratmann & Axel Gandy

  • Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark

    Samir Bhatt

  • Barking, Havering and Redbridge University Hospitals NHS Trust, Barking, UK

    Cherian Koshy & Amy Ash

  • Basingstoke Hospital, Basingstoke, UK

    Emma Wise, Nathan Moore, Matilde Mori, Nick Cortes, Jessica Lynch & Stephen Kidd

  • Belfast Health and Social Care Trust, Belfast, UK

    Derek J. Fairley, Tanya Curran & James P. McKenna

  • Betsi Cadwaladr University Health Board, Betsi Cadwaladr, UK

    Helen Adams

  • Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK

    Christophe Fraser, Tanya Golubchik & David Bonsall

  • Brighton and Sussex University Hospitals NHS Trust, Brighton, UK

    Mohammed O. Hassan-Ibrahim, Cassandra S. Malone & Benjamin J. Cogger

  • Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK

    Michelle Wantoch & Nicola Reynolds

  • Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

    Ben Warne

  • Cardiff and Vale University Health Board, Cardiff, UK

    Joshua Maksimovic, Karla Spellman, Kathryn McCluggage, Michaela John, Robert Beer, Safiah Afifi & Sian Morgan

  • Cardiff University, Cardiff, UK

    Angela Marchbank, Anna Price, Christine Kitchen, Huw Gulliver, Ian Merrick, Joel Southgate, Martyn Guest, Robert Munn, Trudy Workman, Thomas R. Connor, William Fuller & Catherine Bresner

  • Centre for Clinical Infection and Diagnostics Research, St. Thomas’ Hospital and Kings College London, London, UK

    Luke B. Snell & Amita Patel

  • Centre for Clinical Infection and Diagnostics Research, Department of Infectious Diseases, Guy’s and St Thomas’ NHS Foundation Trust, London, UK

    Themoula Charalampous, Gaia Nebbia, Rahul Batra & Jonathan Edgeworth

  • Centre for Enzyme Innovation, University of Portsmouth (PORT), Portsmouth, UK

    Samuel C. Robson & Angela H. Beckett

  • Centre for Genomic Pathogen Surveillance, University of Oxford, Oxford, UK

    David M. Aanensen, Anthony P. Underwood, Corin A. Yeats, Khalil Abudahab, Ben E. W. Taylor & Mirko Menegazzo

  • Clinical Microbiology Department, Queens Medical Centre, Nottingham, UK

    Gemma Clark, Wendy Smith, Manjinder Khakh, Vicki M. Fleming, Michelle M. Lister, Hannah C. Howson-Wells, Louise Berry, Tim Boswell, Amelia Joseph, Iona Willingham & Carl Jones

  • Clinical Microbiology, University Hospitals of Leicester NHS Trust, Leicester, UK

    Christopher Holmes, Paul Bird, Thomas Helmer, Karlie Fallon & Julian Tang

  • County Durham and Darlington NHS Foundation Trust, Durham, UK

    Veena Raviprakash, Sharon Campbell, Nicola Sheriff, Victoria Blakey & Lesley-Anne Williams

  • Deep Seq, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK

    Matthew W. Loose, Nadine Holmes, Christopher Moore, Matthew Carlile, Victoria Wright, Fei Sang & Johnny Debebe

  • Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK

    Francesc Coll

  • Department of Infectious Diseases, King’s College London, London, UK

    Adrian W. Signell, Gilberto Betancor & Harry D. Wilson

  • Department of Microbiology, Kettering General Hospital, Kettering, UK

    Sahar Eldirdiri, Anita Kenyon & Thomas Davis

  • Department of Zoology, University of Oxford, Oxford, UK

    Oliver G. Pybus, Louis du Plessis, Alex E. Zarebski, Jayna Raghwani, Moritz U. G. Kraemer, Sarah Francois, Stephen W. Attwood, Tetyana I. Vasylyeva, Marina Escalera Zamudio & Bernardo Gutierrez

  • Departments of Infectious Diseases and Microbiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

    M. Estee Torok & William L. Hamilton

  • Division of Virology, Department of Pathology, University of Cambridge, Cambridge, UK

    Ian G. Goodfellow, Grant Hall, Aminu S. Jahun, Yasmin Chaudhry, Myra Hosmillo, Malte L. Pinckert & Iliana Georgana

  • East Kent Hospitals University NHS Foundation Trust, Canterbury, UK

    Samuel Moses & Hannah Lowe

  • East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK

    Luke Bedford

  • Gateshead Health NHS Foundation Trust, Gateshead, UK

    Jonathan Moore & Susanne Stonehouse

  • Genomics Innovation Unit, Guy’s and St. Thomas’ NHS Foundation Trust, London, UK

    Chloe L. Fisher & Ali R. Awan

  • Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK

    John BoYes

  • Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK

    Judith Breuer, Kathryn Ann Harris, Julianne Rose Brown, Divya Shah, Laura Atkinson, Jack C. D. Lee & Nathaniel Storey

  • Guy’s and St. Thomas’ BRC, London, UK

    Flavia Flaviani

  • Guy’s and St. Thomas’ Hospitals, London, UK

    Adela Alcolea-Medina

  • Hampshire Hospitals NHS Foundation Trust, Winchester, UK

    Rebecca Williams & Gabrielle Vernet

  • Health Data Research UK Cambridge, Cambridge, UK

    Michael R. Chapman

  • Health Services Laboratories, London, UK

    Lisa J. Levett, Judith Heaney, Wendy Chatterton & Monika Pusok

  • Heartlands Hospital, Birmingham, UK

    Li Xu-McCrae

  • Hub for Biotechnology in the Built Environment, Northumbria University, Newcastle-upon-Tyne, UK

    Darren L. Smith, Matthew Bashton & Gregory R. Young

  • Imperial College Hospitals NHS Trust, London, UK

    Alison Holmes, Paul Anthony Randell, Alison Cox, Pinglawathee Madona, Frances Bolt, James Price & Siddharth Mookerjee

  • Imperial College London, London, UK

    Manon Ragonnet-Cronin, Fabricia F. Nascimento, David Jorgensen, Igor Siveroni, Rob Johnson, Olivia Boyd, Lily Geidelberg, Erik M. Volz, Aileen Rowan & Graham P. Taylor

  • Institute of Biodiversity, Animal Health and Comparative Medicine, Glasgow, UK

    Katherine L. Smollett

  • King’s College London, London, UK

    Rocio T. Martinez Nunez

  • Liverpool Clinical Laboratories, Liverpool, UK

    Jenifer Mason, Trevor I. Robinson, Elaine O’Toole, Joanne Watts, Cassie Breen & Angela Cowell

  • Maidstone and Tunbridge Wells NHS Trust, Maidstone, UK

    Graciela Sluga

  • Manchester University NHS Foundation Trust, Manchester, UK

    Nicholas W. Machin, Shazaad S. Y. Ahmad & Ryan P. George

  • Microbiology Department, Wye Valley NHS Trust, Hereford, UK

    Fenella Halstead, Venkat Sivaprakasam & Wendy Hogsden

  • MRC Biostatistics Unit, University of Cambridge, Cambridge, UK

    Chris J. Illingworth & Chris Jackson

  • MRC-University of Glasgow Centre for Virus Research, Glasgow, UK

    Emma C. Thomson, James G. Shepherd, Patawee Asamaphan, Marc O. Niebel, Kathy K. Li, Rajiv N. Shah, Natasha G. Jesudason, Lily Tong, Alice Broos, Daniel Mair, Jenna Nichols, Stephen N. Carmichael, Kyriaki Nomikou, Elihu Aranday-Cortes, Natasha Johnson, Igor Starinskij, Ana da Silva Filipe, David L. Robertson, Richard J. Orton, Joseph Hughes, Sreenu Vattipally, Joshua B. Singer & Seema Nickbakhsh

  • National Infection Service, PHE and Leeds Teaching Hospitals Trust, Leeds, UK

    Antony D. Hale, Louissa R. Macfarlane-Smith, Katherine L. Harper & Holli Carden

  • Newcastle Hospitals NHS Foundation Trust, Newcastle, UK

    Yusri Taha, Brendan A. I. Payne, Shirelle Burton-Fanning, Sheila Waugh, Jennifer Collins & Gary Eltringham

  • Newcastle University, Newcastle, UK

    Steven Rushton & Sarah O’Brien

  • NHS Greater Glasgow and Clyde, Glasgow, UK

    Amanda Bradley, Alasdair Maclean, Guy Mollett & Rachel Blacow

  • NHS Lothian, Edinburgh, UK

    Kate E. Templeton, Martin P. McHugh, Rebecca Dewar & Elizabeth Wastenge

  • Norfolk and Norwich University Hospital, Norwich, UK

    Samir Dervisevic, Rachael Stanley, Emma J. Meader & Lindsay Coupland

  • Norfolk County Council, Norwich, UK

    Louise Smith

  • North Cumbria Integrated Care NHS Foundation Trust, Carlisle, UK

    Clive Graham, Edward Barton, Debra Padgett & Garren Scott

  • North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees, UK

    Emma Swindells & Jane Greenaway

  • Northumbria University, Newcastle-upon-Tyne, UK

    Andrew Nelson, Clare M. McCann & Wen C. Yew

  • Oxford University Hospitals NHS Foundation Trust, Oxford, UK

    Monique Andersson, Timothy Peto, Anita Justice, David Eyre & Derrick Crook

  • PathLinks, Northern Lincolnshire & Goole NHS Foundation Trust, Scunthorpe, UK

    Tim J. Sloan, Nichola Duckworth & Sarah Walsh

  • Portsmouth Hospitals University NHS Trust, Portsmouth, UK

    Anoop J. Chauhan, Sharon Glaysher, Kelly Bicknell, Sarah Wyllie, Scott Elliott, Allyson Lloyd & Robert Impey

  • Princess Alexandra Hospital Microbiology Department, Harlow, UK

    Nick Levene & Lynn Monaghan

  • Public Health Agency, Belfast, UK

    Declan T. Bradley & Tim Wyatt

  • Public Health England, Clinical Microbiology and Public Health Laboratory, Cambridge, UK

    Martin D. Curran & Surendra Parmar

  • Public Health Scotland, Glasgow, UK

    Matthew T. G. Holden & Sharif Shaaban

  • Public Health Wales NHS Trust, Cardiff, UK

    Alec Birchley, Alexander Adams, Alisha Davies, Amy Gaskin, Amy Plimmer, Bree Gatica-Wilcox, Caoimhe McKerr, Catherine Moore, Chris Williams, David Heyburn, Elen De Lacy, Ember Hilvers, Fatima Downing, Giri Shankar, Hannah Jones, Hibo Asad, Jason Coombes, Joanne Watkins, Johnathan M. Evans, Laia Fina, Laura Gifford, Lauren Gilbert, Lee Graham, Malorie Perry, Mari Morgan, Matthew Bull, Michelle Cronin, Nicole Pacchiarini, Noel Craine, Rachel Jones, Robin Howe, Sally Corden, Sara Rey, Sara Kumziene-Summerhayes, Sarah Taylor, Simon Cottrell, Sophie Jones & Sue Edwards

  • Quadram Institute Bioscience, Norwich, UK

    Justin O’Grady, Andrew J. Page, Alison E. Mather, David J. Baker, Steven Rudder, Alp Aydin, Gemma L. Kay, Alexander J. Trotter, Nabil-Fareed Alikhan, Leonardo de Oliveira Martins, Thanh Le-Viet & Lizzie Meadows

  • Queen Elizabeth Hospital, Birmingham, UK

    Anna Casey & Liz Ratcliffe

  • Queen’s University Belfast, Belfast, UK

    David A. Simpson, Zoltan Molnar, Thomas Thompson & Erwan Acheson

  • Royal Devon and Exeter NHS Foundation Trust, Exeter, UK

    Jane A. H. Masoli, Bridget A. Knight, Sian Ellard, Cressida Auckland & Christopher R. Jones

  • Royal Free NHS Trust, London, UK

    Tabitha W. Mahungu, Dianne Irish-Tavares, Tanzina Haque, Jennifer Hart & Eric Witele

  • Sandwell and West Birmingham NHS Trust, Birmingham, UK

    Melisa Louise Fenton, Ashok Dadrah, Amanda Symmonds & Tranprit Saluja

  • School of Biological Sciences, University of Portsmouth (PORT), Portsmouth, UK

    Yann Bourgeois & Garry P. Scarlett

  • School of Pharmacy and Biomedical Sciences, University of Portsmouth (PORT), Portsmouth, UK

    Katie F. Loveson, Salman Goudarzi, Christopher Fearn, Kate Cook, Hannah Dent & Hannah Paul

  • Sheffield Teaching Hospitals, Sheffield, UK

    David G. Partridge, Mohammad Raza, Cariad Evans & Kate Johnson

  • South Tees Hospitals NHS Foundation Trust, Newcastle, UK

    Steven Liggett, Paul Baker, Stephen Bonner & Sarah Essex

  • Swansea University, Swansea, UK

    Ronan A. Lyons

  • University Hospitals Southampton NHS Foundation Trust, Southampton, UK

    Kordo Saeed, Adhyana I. K. Mahanama, Buddhini Samaraweera, Siona Silveira, Emanuela Pelosi, Eleri Wilson-Davies, Jacqui A. Prieto & Sarah Jeremiah

  • University College London, London, UK

    Rachel J. Williams, Mark Kristiansen, Sunando Roy, Charlotte A. Williams, Marius Cotic, Nadua Bayzid, Adam P. Westhorpe, John A. Hartley, Riaz Jannoo, Helen L. Lowe, Angeliki Karamani & Leah Ensell

  • University Hospitals Coventry and Warwickshire, Coventry, UK

    Dimitris Grammatopoulos, Sarojini Pandey, Lisa Berry & Katie Jones

  • University of Birmingham, Birmingham, UK

    Alex Richter & Andrew Beggs

  • University of Birmingham Turnkey Laboratory, Birmingham, UK

    Angus Best, Benita Percival, Jeremy Mirza, Oliver Megram, Megan Mayhew, Liam Crawford, Fiona Ashcroft, Emma Moles-Garcia & Nicola Cumley

  • University of Brighton, Brighton, UK

    Colin P. Smith, Giselda Bucca & Andrew R. Hesketh

  • University of Cambridge, Cambridge, UK

    Beth Blane, Sophia T. Girgis, Danielle Leek, Sushmita Sridhar, Sally Forrest, Claire Cormie, Harmeet K. Gill, Joana Dias, Ellen E. Higginson, Mailis Maes, Jamie Young, Leanne M. Kermack, Ravi Kumar Gupta, Catherine Ludden, Sharon J. Peacock, Sophie Palmer, Carol M. Churcher, Nazreen F. Hadjirin, Alessandro M. Carabelli, Ellena Brooks, Kim S. Smith, Katerina Galai, Georgina M. McManus & Chris Ruis

  • University of East Anglia, Norwich, UK

    Rose K. Davidson

  • University of Edinburgh, Edinburgh, UK

    Andrew Rambaut, Thomas Williams, Carlos E. Balcazar, Michael D. Gallagher, Áine O’Toole, Stefan Rooke, Verity Hill, Kathleen A. Williamson & Thomas D. Stanton

  • University of Exeter, Exeter, UK

    Stephen L. Michell, Claire M. Bewshea, Ben Temperton, Michelle L. Michelsen, Joanna Warwick-Dugdale, Robin Manley, Audrey Farbos, James W. Harrison, Christine M. Sambles, David J. Studholme & Aaron R. Jeffries

  • University of Liverpool, Liverpool, UK

    Alistair C. Darby, Julian A. Hiscox, Steve Paterson, Miren Iturriza-Gomara, Kathryn A. Jackson, Anita O. Lucaci, Edith E. Vamos, Margaret Hughes, Lucille Rainbow, Richard Eccles, Charlotte Nelson, Mark Whitehead, Lance Turtle, Sam T. Haldenby, Richard Gregory, Matthew Gemmell, Claudia Wierzbicki & Hermione J. Webster

  • University of Sheffield, Sheffield, UK

    Thushan I. de Silva, Nikki Smith, Adrienn Angyal, Benjamin B. Lindsey, Danielle C. Groves, Luke R. Green, Dennis Wang, Timothy M. Freeman, Matthew D. Parker, Alexander J. Keeley, Paul J. Parsons, Rachel M. Tucker, Rebecca Brown, Matthew Wyles, Max Whiteley, Peijun Zhang, Marta Gallis & Stavroula F. Louka

  • University of Warwick, Warwick, UK

    Chrystala Constantinidou, Meera Unnikrishnan, Sascha Ott, Jeffrey K. J. Cheng, Hannah E. Bridgewater, Lucy R. Frost, Grace Taylor-Joyce, Richard Stark, Laura Baxter, Mohammad T. Alam & Paul E. Brown

  • University of Cambridge, Cambridge, UK

    Dinesh Aggarwal

  • Viapath, London, UK

    Alberto C. Cerda, Tammy V. Merrill & Rebekah E. Wilson

  • Guy’s and St Thomas’ NHS Foundation Trust, London, UK

    Alberto C. Cerda, Tammy V. Merrill & Rebekah E. Wilson

  • King’s College Hospital NHS Foundation Trust, London, UK

    Alberto C. Cerda, Tammy V. Merrill & Rebekah E. Wilson

  • Virology, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK

    Patrick C. McClure, Joseph G. Chappell, Theocharis Tsoleridis & Jonathan Ball

  • Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK

    David Buck, John A. Todd, Angie Green, Amy Trebes, George MacIntyre-Cockett & Mariateresa de Cesare

  • West of Scotland Specialist Virology Centre, NHS Greater Glasgow and Clyde, Glasgow, UK

    Rory N. Gunson

  • Conceptualization: E.V., S.B., A.G., S.M., N.M.F., M.C., S.H., J.C.B., D.P.K., A.R.; writing (first draft): E.V., S.F., S.B., A.G., O.R., S.M., R.J., A.R., N.M.F.; writing (review and editing): E.V., S.F., S.B., A.G., O.R., S.M., R.J., N.M.F., M.R.-C., D.J.L., M.C., S.H., J.C.B., K.G., C.V.A., J.T.M., V.H., B.J., Á.O’T.; analysis: E.V., S.F., S.B., A.G., O.R., S.M., R.J., N.M.F., L.G., D.J., M.C., R.M., N.G., J.C.B., J.S., A.R.; methodology: E.V., S.F., S.B., A.G., O.R., S.M., R.J., N.M.F., A.R.; data generation: S.H., S.M., R.J., O.B., M.C., R.M., N.G., I.H., G.D., N.J.L., J.C.B., D.P.K., R.A., C.V.A., S.G., W.R.H.,D.K.J., J.S., O.B., K.G., J.T.M., V.H., B.J., Á.O’T., A.R.; software: E.V., S.F., A.G., S.M., R.J., N.M.F., R.A., S.G., K.G.; validation: E.V., S.B., S.M., N.M.F.; visualization: E.V., S.F., S.B., O.R., S.M., M.R.-C.; supervision: E.V., S.B., O.R., N.M.F., A.R.; funding acquisition: E.V., S.F., S.B., A.G., N.M.F., N.J.L., A.R.

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